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On September 26, UCLA researcher reported the outcome of a study, which indicated that Asians who are struggling with alcoholism may benefit especially from naltrexone, certainly one of three medications licensed by the U.S. Food and Drug Administration (FDA) for that treatment of alcoholism. Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a very particular mutation which makes them more likely to benefit from naltrexone, in contrast to about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director in the UCLA Addictions Laboratory. The findings are available online ( in the journal Neuropsychopharmacology and will also be published in a upcoming print edition from the journal.

Using two separate drugs to lose weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight loss and the people that go through it one should err to the side of caution and allow the FDA do its job and demand some study be done so the public knows the side effects and risks of the medications before we drive them. Keep in mind that drug companies are in business to generate money and that they would say anything to keep people on their own medications.

Researchers found that participants using this drug for a year, lost weight within 4 weeks and have kept the weight off through the 56 weeks with the study. Contrave can be a combination with the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which might be made up of more than one active ingredient, which can make them more potent and safer.

Combo-pilling will be the newest fad or even better the newest in the future under scrutiny and thus it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is now popular could be the fact that since right now there aren't any long term prescription slimming capsules that have been licensed by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be authorized by the FDA.

Seizures can be a side effect with Contrave and really should not be taken in people with seizure disorders. The drug may also raise blood pressure and heartrate, and mustn't be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise hypertension and heartbeat and must not be used in patients with uncontrolled high blood pressure level, and also by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients with a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients for the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.


The most common unwanted side effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.

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